In a dominating performance to kick off the 2027 season, the Arizona Cardinals defeated the Pittsburgh Steelers 45-10. This Week 1 matchup set the tone for both teams as they look to establish their identities early in the campaign. The Cardinals showcased their offensive firepower while the Steelers struggled to keep pace. Jeremiyah Love was the standout star for Arizona, racking up an impressive 288 rushing yards and finding the end zone multiple times. Baker Mayfield, despite his team's struggles, threw for 218 yards and a touchdown, while Darnell Washington led the Steelers' receiving corps with 116 yards. However, it was clear that the Cardinals' running game was the focal point of their offensive strategy, overpowering the Steelers' defense throughout the contest. Defensively, the Cardinals were relentless, with Sean Murphy-Bunting making a significant impact by snagging three interceptions, effectively stifling any momentum the Steelers attempted to build. Josh Sweat added to the pressure with a sack, and Budda Baker led the team with four total tackles. The game turned decisively in Arizona's favor after Murphy-Bunting's second interception, which set up a scoring drive that extended their lead and left Pittsburgh scrambling for answers.