In a tightly contested matchup, the Arizona Cardinals narrowly defeated the San Francisco 49ers, 17-13, in Week 3 of the 2026 season. Both teams were looking to establish momentum early in the season, but it was the Cardinals who secured the crucial victory on the road. Brock Purdy of the 49ers put up impressive numbers, throwing for 284 yards and a touchdown, but it was Jeremiyah Love of the Cardinals who stole the show. Love not only led the team with 15 rushing yards but also racked up an astounding 192 receiving yards, proving to be a dual-threat that the San Francisco defense struggled to contain throughout the game. Defensively, the Cardinals stepped up when it mattered most, with Mack Wilson Sr. leading the charge with five total tackles. The turning point came late in the fourth quarter when Andrew Wingard intercepted Purdy, giving Arizona the opportunity to seal the game and secure the victory. With Josh Sweat contributing a sack, the Cardinals' defense proved pivotal, stifling the 49ers' attempts to mount a comeback.