In a commanding performance to kick off the 2027 season, the Arizona Cardinals topped the Los Angeles Rams 25-10. With both teams looking to set the tone for the year, the Cardinals showcased their offensive firepower while the Rams struggled to keep pace. Quarterback Arch Manning was the standout performer, throwing for 361 yards and two touchdowns, while wide receiver Wan'Dale Robinson emerged as his favorite target, racking up an impressive 144 receiving yards. On the ground, the Rams' Travis Etienne Jr. managed a respectable 69 rushing yards, but it wasn't enough to spark a comeback for Los Angeles. Defensively, the Cardinals were relentless, particularly linebacker Terrel Bernard, who led the team with 10 total tackles. The turning point came when Arizona's Arvell Reese recorded 1.5 sacks, disrupting the Rams' rhythm and forcing them into tough situations. Despite a lone interception from Derwin James Jr., the Rams couldn't overcome the Cardinals' defensive pressure, ultimately sealing their fate in the season opener.