In a dominant display, the San Francisco 49ers defeated the Seattle Seahawks 37-6 in Week 5 of the 2026 season. With this victory, the 49ers continue to assert their dominance in the division, further solidifying their playoff ambitions early in the year. Brock Purdy led the charge for San Francisco, throwing for 332 yards and a touchdown, showcasing his ability to move the ball effectively. Christian McCaffrey added a stellar performance on the ground with 101 rushing yards, while Christian Kirk emerged as a key target, racking up 117 receiving yards. Their combined efforts propelled the 49ers to a commanding offensive performance. Defensively, the 49ers were relentless, with Fred Warner leading the way with eight total tackles, ensuring Seattle's offense struggled to find any rhythm. The turning point came late in the first half, when San Francisco's defense stifled a Seahawks drive, forcing a turnover that shifted momentum firmly in their favor. With this victory, the 49ers not only showcased their offensive firepower but also demonstrated their defensive prowess, making a strong statement in the NFC.