In a commanding performance, the San Francisco 49ers topped the Arizona Cardinals 35-14 in Week 3 of the 2026 season. With this victory, the 49ers solidified their position in the division, showcasing their offensive prowess against a struggling Cardinals defense. Brock Purdy was the star of the show, throwing for an impressive 358 yards and five touchdowns, demonstrating pinpoint accuracy and poise under pressure. De'Zhaun Stribling was his favorite target, racking up 171 receiving yards, while Jeremiyah Love of the Cardinals made his mark on the ground with 160 rushing yards, but it wasn’t enough to keep pace with San Francisco’s explosive attack. Defensively, the 49ers were able to disrupt Arizona's rhythm, with Fred Warner leading the team with four tackles. Mack Wilson Sr. provided a spark for the Cardinals with two sacks, but the turning point came when the 49ers' defense stifled a crucial drive in the second half, allowing Purdy and the offense to extend their lead and ultimately seal the game.