In a commanding performance, the Indianapolis Colts triumphed over the Houston Texans with a final score of 42-21 in Week 3 of the 2026 season. The Colts improved their record, showcasing their dominance as they continue to assert themselves as contenders in the league. Peyton Manning led the charge for Indianapolis, throwing for an impressive 363 yards and two touchdowns, solidifying his status as a key offensive force. Marvin Harrison was his primary target, racking up 124 receiving yards, while Jordan Mason contributed significantly on the ground with 74 rushing yards. Together, they formed a potent offensive unit that consistently exploited the Texans' defense. Defensively, the Colts were effective in stifling the Texans’ attempts to rally, with Kristian Fulton’s interception proving to be a critical moment in the game. Malcolm Roach added pressure with a sack, disrupting the Texans' offensive rhythm. Ultimately, the Colts’ defense played a crucial role in maintaining their lead and ensuring the victory as they kept Houston at bay throughout the contest.