In a commanding performance, the San Francisco 49ers topped the Seattle Seahawks 31-10 in Week 5 of the 2026 season. This victory solidifies the 49ers' position in the playoff race, showcasing their dominance in the NFC West. Brock Purdy led the charge for San Francisco, throwing for a touchdown and managing the game effectively, while Christian McCaffrey was a workhorse on the ground, racking up 121 rushing yards and punctuating the offense with key plays. Despite Jalen Milroe's efforts for Seattle, who threw for 142 yards, the Seahawks struggled to find the end zone. Defensively, the 49ers made their presence felt, with Alfred Collins recording a crucial sack that disrupted Seattle’s rhythm. The game shifted decisively in the second half, as San Francisco's defense stifled the Seahawks' drives, allowing the 49ers to pull away and secure the victory. Devon Witherspoon led Seattle’s defensive efforts with 11 tackles and an interception, but it wasn’t enough to turn the tide in this matchup.