In a commanding performance, the Detroit Lions topped the Buffalo Bills 42-13 in Week 2 of the 2026 season. The Lions aimed to establish their dominance early in the season, and they certainly delivered with this decisive victory. Jared Goff led the charge for Detroit, throwing for 3 touchdowns while accumulating 238 passing yards. Jahmyr Gibbs contributed significantly on the ground, rushing for 86 yards and helping to keep the Buffalo defense on its heels. Although Josh Allen threw for 284 yards, it was not enough to match the Lions' offensive firepower, with Joshua Palmer being the standout receiver for Buffalo, racking up 105 receiving yards. Defensively, the Lions made their mark with a stellar performance, highlighted by Starling Thomas V's three interceptions. Alim McNeill added pressure with a sack, disrupting Buffalo's offensive rhythm throughout the game. The turning point came in the second quarter when Thomas V's first interception led to a quick touchdown, shifting the momentum solidly in favor of Detroit and ultimately sealing the Bills' fate.