In a commanding performance, the San Francisco 49ers defeated the Seattle Seahawks 34-10 in Week 5 of the 2027 season. The victory solidifies the 49ers' position in the playoff hunt, showcasing their dominance both offensively and defensively against a division rival. Brock Purdy led the charge for San Francisco, throwing for 304 yards and two touchdowns, demonstrating impressive poise in the pocket. Meanwhile, Christian McCaffrey contributed significantly on the ground, racking up 105 rushing yards, while Mike Evans was a standout in the receiving corps with a remarkable 172 receiving yards. The 49ers' offense was efficient and relentless, making it difficult for the Seahawks to keep pace. Defensively, the 49ers made their mark with key plays, including an interception from Deommodore Lenoir that shifted momentum in their favor. The turning point came in the second quarter when Lenoir's pick set up a touchdown, extending San Francisco's lead and leaving the Seahawks struggling to recover. Overall, the 49ers' ability to pressure the Seahawks and capitalize on turnovers proved to be the difference in this decisive matchup.