In a tightly contested matchup, the Detroit Lions topped the Buffalo Bills 17-10 in Week 2 of the 2026 season. The stakes were high as both teams sought to establish momentum early in the year, but it was the Lions who emerged victorious on the road. Jared Goff led the Lions' offensive attack, throwing for 252 yards and a touchdown, showcasing his ability to move the ball effectively. Jahmyr Gibbs contributed significantly on the ground, racking up 96 rushing yards, while Amon-Ra St. Brown was the primary target in the passing game, finishing with 81 receiving yards. This balanced offensive performance allowed Detroit to maintain control and capitalize on key moments. Defensively, the Lions made critical plays that shaped the outcome of the game. Aidan Hutchinson's sack put pressure on the Bills' offense at crucial junctures, while D.J. Reed's interception sealed the win for Detroit late in the fourth quarter. The Lions' defense stepped up when it mattered most, stifling Buffalo's attempts to mount a comeback and securing the hard-fought victory.