In a dominating performance, the San Francisco 49ers defeated the Miami Dolphins 35-0 in Week 2 of the 2026 season. This win not only boosts the 49ers' record but also sends a clear message to the rest of the league about their formidable capabilities this year. Brock Purdy was on fire for San Francisco, throwing for 224 yards and four touchdowns, showcasing his accuracy and decision-making throughout the game. Jerry Rice led the receiving corps with an impressive 108 yards, consistently finding space in the Dolphins' secondary. Meanwhile, the running game struggled slightly, with Christian McCaffrey managing just seven rushing yards; however, the passing attack more than made up for it. The 49ers' defense was relentless, with Ephesians Prysock making a game-changing impact by intercepting three passes, stifling any hopes of a Dolphins comeback. Mykel Williams added to the pressure with 1.5 sacks, disrupting Miami’s offensive rhythm. The turning point came early when Prysock's first interception set up a quick touchdown, setting the tone for a lopsided affair that Miami could never recover from.