In a decisive showdown in Week 14 of the 2026 season, the San Francisco 49ers topped the Los Angeles Rams with a final score of 42-21. With playoff implications on the line, the 49ers showcased their dominance, solidifying their position in the postseason race while the Rams faced a critical setback. Dak Prescott led the 49ers' offensive charge with a stellar performance, throwing for three touchdowns and effectively managing the game. On the ground, D'Andre Swift contributed with 67 rushing yards, helping to keep the Rams' defense off balance. Meanwhile, Malik Nabers stood out for the Rams, racking up 119 receiving yards, but it wasn’t enough to overcome San Francisco’s firepower. Defensively, the 49ers were impactful, with Jack Campbell leading the team in tackles with six. Andrew Van Ginkel added pressure with a sack, while Zyon McCollum came up big with an interception that shifted momentum in the first half. This turnover proved to be a turning point, allowing the 49ers to extend their lead and maintain control throughout the game.