In a decisive matchup in Week 10 of the 2026 season, the Arizona Cardinals topped the Los Angeles Rams with a final score of 37-21. This victory was crucial as the Cardinals aimed to solidify their playoff positioning, while the Rams sought to stay competitive in the division race. Trevor Lawrence showcased his skills for the Rams, throwing for 296 yards and two touchdowns, while also connecting with Malik Nabers, who amassed 101 receiving yards. Josh Jacobs contributed significantly on the ground, rushing for 104 yards, but despite their efforts, the Rams couldn't overcome the Cardinals' offensive firepower. The Cardinals' defense played a pivotal role in this victory, highlighted by Quinyon Mitchell's standout performance, which included five tackles and an interception. Will Anderson Jr. added pressure with 1.5 sacks, disrupting the Rams' rhythm. The game's turning point came late in the second quarter when Mitchell's interception shifted momentum, allowing Arizona to convert it into a touchdown and ultimately control the pace for the rest of the game.