In a thrilling showdown, the Detroit Lions narrowly defeated the Arizona Cardinals 45-42 in Week 5 of the 2026 season. Both teams were looking to solidify their standing in the division, but it was the Lions who ultimately came out on top in this high-scoring affair. Jared Goff led the Lions' offensive charge, throwing for an impressive 396 yards and finding the end zone five times. His favorite target, Amon-Ra St. Brown, shined with 163 receiving yards, proving to be a constant threat. The Lions showcased their offensive prowess, scoring effectively and keeping the pressure on the Cardinals throughout the game. On the defensive side, the Lions made crucial plays when it mattered most, including an interception from Kerby Joseph that shifted momentum back to Detroit. While the Cardinals' Mack Wilson Sr. recorded 14 total tackles and Walter Nolen III added a sack, the Lions' ability to create turnovers proved vital. The turning point came late in the game when Goff connected with St. Brown for a touchdown that sealed the deal, allowing Detroit to hold off a late surge from Arizona.