In a dominant display, the Detroit Lions decisively defeated the Buffalo Bills 38-7 in Week 2 of the 2026 season, showcasing their potential as a playoff contender. This matchup was crucial for both teams, with the Lions looking to build momentum while the Bills aimed to bounce back after a shaky start to the season. Offensively, the Lions were led by Isiah Pacheco, who racked up 62 rushing yards, providing a steady ground game that kept the Bills’ defense on its heels. Quarterback play was critical, with the Lions consistently finding openings and putting points on the board. Meanwhile, Josh Allen threw for 184 yards for Buffalo, but struggled to convert drives into touchdowns, ultimately hampering their efforts. Detroit's defense was instrumental in this lopsided affair, particularly with Levi Onwuzurike recording a sack and Brian Branch snagging an interception. The turning point came when Branch's interception halted a promising Bills drive, allowing the Lions to capitalize and extend their lead. Dorian Williams led the Bills with 13 tackles, but it wasn't enough to counter the Lions' relentless pressure and scoring efficiency.