In a dominating performance, the San Francisco 49ers topped the Arizona Cardinals 62-28 in Week 3 of the 2026 season. This victory not only solidifies the 49ers' position within the division but also showcases their offensive firepower and defensive prowess against a struggling Cardinals squad. Brock Purdy was the standout performer for San Francisco, throwing for an impressive 387 yards and five touchdowns, displaying precision and poise throughout the game. George Kittle complemented Purdy's efforts with 125 receiving yards, consistently finding openings in the Cardinals' defense. On the ground, Jeremiyah Love of Arizona put up a remarkable 255 rushing yards, but it was not enough to keep pace with the 49ers' prolific scoring. Defensively, the 49ers were instrumental in securing the win, with Jack Jones making a significant impact by recording two interceptions. Fred Warner added to the defensive effort with a sack, while Dre Greenlaw led the team in tackles with five. The turning point came when Jones picked off a pass and returned it deep into Cardinals territory, setting up a touchdown that pushed the 49ers' lead to an insurmountable level.