In a dominant display, the Denver Broncos toppled the San Francisco 49ers with a final score of 56-27, solidifying their status as a contender in the 2026 season. This Week 4 matchup showcased the Broncos' high-octane offense, which proved too much for the 49ers to handle, as Denver aims to build momentum heading into the heart of the season. Anthony Richardson Sr led the charge for the Broncos, throwing for an impressive 304 yards and four touchdowns, showcasing his ability to command the field. He connected seamlessly with Isaac TeSlaa, who racked up 110 receiving yards, providing a significant threat down the field. Meanwhile, Saquon Barkley stood out for San Francisco, gaining 217 rushing yards, but ultimately, the 49ers couldn't keep pace with Denver's explosive scoring. Defensively, the Broncos made key plays that shifted the momentum in their favor. Jonathon Cooper recorded a sack, while Riq Woolen's interception added to the Broncos' dominance on that side of the ball. The turning point came in the second quarter when a turnover led to a quick Denver touchdown, effectively putting the game out of reach for San Francisco.