In a commanding performance, the Arizona Cardinals topped the Seattle Seahawks 49-17 in Week 2 of the 2026 season. With this victory, the Cardinals not only secured their second win of the season but also sent a strong message to the rest of the league about their offensive firepower. Leading the charge for Arizona was quarterback Michael Penix Jr., who threw for 315 yards and three touchdowns, showcasing his ability to connect with his receivers effectively. Ja'Marr Chase was a key target, racking up 99 receiving yards, while the Seahawks' Christian McCaffrey managed to shine on the ground with 115 rushing yards despite the lopsided score. Defensively, the Cardinals were anchored by Josh Sweat, who recorded a sack, contributing to a relentless pass rush that pressured Seattle's offense throughout the game. The turning point came early in the second quarter when Penix Jr. threw a touchdown pass that shifted the momentum firmly in Arizona's favor, allowing them to dominate the rest of the game and solidify their lead.