In a thrilling matchup, the Arizona Cardinals narrowly defeated the San Francisco 49ers by a score of 30-24, solidifying their position in the early weeks of the 2026 season. With both teams vying for momentum, the stakes were high as they faced off in this pivotal Week 3 clash. Brock Purdy shone for the 49ers, racking up 279 passing yards and throwing three touchdown passes, showcasing his ability to lead the offense effectively. De'Zhaun Stribling was his favorite target, amassing an impressive 150 receiving yards, while Christian McCaffrey contributed a solid ground game with 88 rushing yards. Despite the offensive fireworks from San Francisco, it was the Cardinals' timely plays that made the difference. On the defensive side, Josh Sweat of the Cardinals stood out with 1.5 sacks, applying crucial pressure on Purdy throughout the game. Azareye'h Thomas added a game-changing interception that shifted momentum back to Arizona, ultimately sealing the victory. The turning point came late in the fourth quarter when Thomas's pick set up a decisive touchdown, allowing the Cardinals to hold off a last-ditch effort from the 49ers.