In a commanding performance, the Los Angeles Rams topped the San Francisco 49ers with a final score of 38-13 in Week 1 of the 2026 season. The Rams showcased their offensive firepower right out of the gate, setting the tone for what they hope will be a successful season. Leading the charge for the Rams was quarterback Matthew Stafford, who threw for an impressive 346 yards and three touchdowns. Puka Nacua was his favorite target, racking up 123 receiving yards, while Christian McCaffrey led the 49ers on the ground with 69 rushing yards, but it wasn't enough to keep pace with the Rams' explosive offense. Defensively, Myles Garrett made his presence felt with 1.5 sacks, disrupting the 49ers' rhythm and helping to stifle any comeback attempts. The Rams' defense effectively capitalized on turnovers and key stops, with the game's turning point coming in the second quarter when they halted a promising San Francisco drive, leading to a momentum-shifting touchdown shortly thereafter. The Rams look poised to build on this strong start as they move deeper into the season.