In a commanding performance, the Los Angeles Rams topped the Arizona Cardinals 45-24 in Week 6 of the 2026 season. With this victory, the Rams solidify their position as a formidable contender in their division, showcasing both offensive firepower and defensive resilience. Matthew Stafford led the charge for Los Angeles, throwing for 349 yards and three touchdowns, while Kyren Williams added a significant ground presence with 126 rushing yards. Puka Nacua proved to be a reliable target, racking up 139 receiving yards and consistently moving the chains for the Rams. Defensively, the Rams made their mark with Myles Garrett leading the way, recording two sacks that disrupted the Cardinals' rhythm. Trent McDuffie’s interception also played a crucial role, as it halted a potential scoring drive and shifted momentum firmly in favor of Los Angeles. With a dominant performance across the board, the Rams demonstrated their ability to control both sides of the ball, creating a defining win in their campaign.