In a thrilling Week 3 matchup of the 2026 season, the San Francisco 49ers topped the Arizona Cardinals with a final score of 41-28. This victory solidifies the 49ers' strong start to the season and showcases their offensive prowess against a competitive divisional rival. Brock Purdy led the charge for San Francisco, throwing for three touchdowns and keeping the chains moving with precision passing. Joe Milton of the Cardinals impressed with 319 passing yards, showcasing his ability to connect downfield, while Jeremiyah Love added a dynamic element to Arizona's ground game with 109 rushing yards. Mike Evans was a standout for the 49ers, racking up 122 receiving yards and proving to be a key target in crucial moments. Defensively, the 49ers made significant contributions that helped secure the win. Ji'Ayir Brown recorded five total tackles, while Osa Odighizuwa added a sack to disrupt Arizona's rhythm. The turning point came when Dre Greenlaw intercepted two passes, shifting momentum firmly in San Francisco's favor and thwarting any potential comeback attempts from the Cardinals.