In a decisive matchup in Week 4 of the 2026 season, the Buffalo Bills secured a commanding victory over the New England Patriots, winning 28-7. The game was crucial for both teams as they sought to establish themselves in the playoff race, but it was Buffalo that showed dominance on both sides of the ball. Offensively, the Bills were led by a strong performance from James Cook III, who rushed for 88 yards and helped set the tone for the game. Quarterback Drake Maye of the Patriots managed to put up 104 passing yards and threw one touchdown, but it was not enough to keep pace with Buffalo's offensive firepower. Romeo Doubs was the standout receiver for New England, racking up 74 yards, yet the Patriots struggled to find consistency overall. Defensively, the Bills made critical plays that shifted the momentum in their favor. Dorian Williams registered a key sack, disrupting Patriots drives at pivotal moments, while Cole Bishop’s interception further solidified Buffalo’s control of the game. The turning point came in the second quarter when the Bills capitalized on a turnover, resulting in a touchdown that extended their lead and left New England fighting an uphill battle for the remainder of the contest.