In a commanding victory, the San Francisco 49ers topped the Seattle Seahawks 44-24 in Week 12 of the 2026 season. With playoff aspirations on the line, the 49ers showcased their dominance, solidifying their position in the postseason race. Brock Purdy was the standout performer for San Francisco, throwing for an impressive 379 yards and five touchdowns, leading a potent offensive attack. Christian McCaffrey added to the offensive fireworks with 121 rushing yards, while De'Zhaun Stribling was a reliable target, racking up 156 receiving yards. This trio was instrumental in keeping the Seahawks' defense on its heels throughout the game. Defensively, the 49ers made key plays that shifted momentum, highlighted by Marques Sigle's interception that halted a potential Seahawks scoring drive. Mykel Williams added pressure with a sack, contributing to a strong defensive performance that limited Seattle's big plays. The turning point came late in the first half when Purdy connected for his third touchdown pass, giving the 49ers a commanding lead that the Seahawks could never recover from.