In a high-scoring showdown, the Detroit Lions topped the Buffalo Bills 42-28, securing their second win of the young season. The stakes were high as both teams aimed to establish early dominance in the league, but it was the Lions who emerged victorious on the road. Jared Goff led the way for Detroit, throwing for three touchdowns while amassing 274 passing yards. Jahmyr Gibbs was a force on the ground, racking up an impressive 173 rushing yards, and Amon-Ra St. Brown showcased his skills with 145 receiving yards. The Lions' offensive unit capitalized on their opportunities, demonstrating a potent mix of rushing and passing that overwhelmed the Bills' defense. On the defensive side, the Lions made critical plays when it mattered most, highlighted by Jack Campbell's two interceptions that shifted momentum in Detroit's favor. The game turned in the second quarter when Campbell's first pick set up a quick touchdown, allowing the Lions to take a commanding lead. Despite Greg Rousseau's two sacks for Buffalo, the Lions' defense ultimately made the key stops to secure the victory, proving decisive in this thrilling matchup.