In a commanding performance, the Buffalo Bills defeated the Detroit Lions 33-6 in Week 2 of the 2026 season. The victory solidifies Buffalo's early-season momentum as they look to establish themselves as contenders in the AFC. Leading the charge for the Bills was quarterback Josh Allen, who threw for 172 yards and two touchdowns, showcasing his ability to make plays when it mattered most. Ty Johnson contributed significantly on the ground with 70 rushing yards, while Khalil Shakir was a key target in the passing game, racking up 77 receiving yards. This offensive firepower proved too much for the Lions to handle. Defensively, the Bills were relentless, highlighted by Greg Rousseau’s two sacks that disrupted Detroit’s rhythm. The turning point came early in the second half when Buffalo's defense stifled a Lions drive deep in their territory, leading to a quick touchdown that extended the lead to 27-6. With a dominant defensive effort, Buffalo ensured that the Lions never found their footing in this matchup.