In a commanding Week 1 matchup, the Buffalo Bills topped the Miami Dolphins 21-7, setting the tone for the 2027 season. Both teams were eager to start strong, but the Bills showcased their dominance right out of the gate. Josh Allen was the standout performer for Buffalo, throwing for 175 yards and one touchdown, effectively leading the offense. James Cook III made significant contributions on the ground, racking up 95 rushing yards, while DJ Moore provided reliable hands in the passing game with 43 receiving yards. Buffalo's defense played a pivotal role in the victory, highlighted by Greg Rousseau's impressive two sacks that disrupted Miami's offensive rhythm. The turning point came in the second quarter when Rousseau's pressure led to a critical turnover, allowing the Bills to capitalize and extend their lead. The Dolphins struggled to respond, managing only one touchdown as Buffalo's defense held firm throughout the game.