The Buffalo Bills secured a decisive 35-14 victory over the Denver Broncos in Week 16 of the 2026 season, solidifying their playoff positioning as the regular season winds down. The Bills showcased their offensive prowess, dominating the field and leaving little doubt about their capabilities heading into the postseason. Josh Allen was the standout performer for Buffalo, throwing for an impressive 378 yards and four touchdowns, effectively leading the team’s offensive charge. Khalil Shakir emerged as his favorite target, racking up 190 receiving yards, while James Cook III added a solid ground game with 64 rushing yards. Together, they formed a lethal combination that kept the Broncos' defense on its heels throughout the game. Defensively, the Bills were relentless, with Greg Rousseau recording three sacks and an interception, making his presence felt at crucial moments. The turning point came in the second quarter when Rousseau's pick set up another touchdown for Buffalo, pushing their lead to 21-7. The Broncos struggled to recover from that momentum shift, unable to counter the Bills' defensive pressure and offensive efficiency.