In a thrilling Week 4 showdown, the Denver Broncos narrowly defeated the San Francisco 49ers, finishing with a final score of 45-43. Both teams fought hard, but the Broncos emerged victorious, maintaining their momentum in the 2026 season while the 49ers look to regroup after a tough loss. Bo Nix was the standout performer for Denver, throwing for an impressive 570 yards and four touchdowns, showcasing his arm strength and precision throughout the game. Marvin Mims Jr. also made a significant impact, racking up 266 receiving yards and providing Nix with a reliable target downfield. Meanwhile, Christian McCaffrey kept the 49ers competitive with a dominant rushing performance, amassing 147 yards on the ground. Defensively, the Broncos held off the 49ers just enough to secure the win, with Brandon Jones leading the way with six total tackles. T.J. Watt contributed with a crucial sack that disrupted San Francisco's rhythm, while Renardo Green's interception for the 49ers highlighted their defensive efforts. The turning point came late in the fourth quarter when the Broncos' defense stifled a potential game-winning drive, preserving their slim lead and clinching the victory.