In a commanding performance, the San Francisco 49ers defeated the Arizona Cardinals 30-6 in Week 3 of the 2026 season. This victory solidified the 49ers' strong start, as they showcased their dominance on both sides of the ball against a struggling Cardinals team. Brock Purdy was the standout on offense, throwing for 207 yards and two touchdowns, effectively leading the 49ers' attack. Christian McCaffrey complemented Purdy’s performance with 79 rushing yards, while De'Zhaun Stribling was a reliable target, racking up 95 receiving yards. The offensive efficiency was a major factor in the lopsided scoreline, allowing San Francisco to control the pace of the game. Defensively, the 49ers were a force to be reckoned with, with Fred Warner leading the charge with 10 total tackles. The turning point came in the second quarter when Nick Bosa recorded two of his three sacks, disrupting the Cardinals' offensive rhythm and forcing crucial turnovers. With consistent pressure and solid tackling, the 49ers' defense stifled Arizona's efforts, ensuring a comfortable win.