In a thrilling shootout that kept fans on the edge of their seats, the San Francisco 49ers narrowly defeated the Arizona Cardinals 65-64 in Week 3 of the 2026 season. Both teams were looking to solidify their positions early in the season, but it was the 49ers who emerged victorious in this high-scoring affair. Brock Purdy was nothing short of sensational for San Francisco, throwing for an astonishing 543 yards and six touchdowns, showcasing his ability to connect with his weapons downfield. Rashee Rice complemented Purdy's performance with a remarkable 304 receiving yards, proving to be a reliable target throughout the game. On the ground, Jeremiyah Love of the Cardinals made his mark with an impressive 369 rushing yards, but ultimately it wasn't enough to secure the win. Defensively, the 49ers made crucial plays when it mattered most. Fred Warner led the charge with six total tackles, while Nick Herbig added a key sack that disrupted the Cardinals' momentum. The game's turning point came late in the fourth quarter when Art Green intercepted a pass, allowing the 49ers to maintain their narrow lead and seal the victory.