The Detroit Lions topped the Arizona Cardinals 42-21 in a decisive Week 5 matchup, solidifying their position in the playoff hunt. With both teams looking to gain momentum, the Lions showcased their offensive prowess, leaving no doubt about their capabilities. Jared Goff led the charge for Detroit, delivering an impressive performance with 347 passing yards and three touchdowns. He found Cedric Tillman frequently, who torched the Cardinals' secondary for 164 receiving yards, providing the Lions with a deep threat throughout the game. Christian McCaffrey added to the offensive effort with 37 rushing yards, contributing to a well-rounded attack that kept Arizona on their heels. Defensively, the Lions made their mark with a standout performance, highlighted by Jack Campbell's eight total tackles and Jared Verse's two sacks. Kerby Joseph's two interceptions were pivotal, shifting the momentum in favor of Detroit and sealing the victory. The turning point came in the second quarter when Joseph picked off a pass, setting up a touchdown that extended the Lions' lead and left the Cardinals struggling to respond.