In a decisive Week 2 matchup, the Buffalo Bills topped the Detroit Lions 28-7, solidifying their position early in the 2026 season. The Bills dominated the game, showcasing their offensive prowess and defensive strength, leaving the Lions searching for answers. Josh Allen spearheaded Buffalo's attack, throwing for 241 yards and two touchdowns, while James Cook III made a significant impact on the ground with 107 rushing yards. Skyler Bell was a standout in the receiving game, racking up 134 yards, proving to be a reliable target for Allen and keeping the Lions' defense on its heels throughout the contest. Defensively, the Bills were formidable, with Bradley Chubb recording two sacks and Dorian Williams snagging an interception, further disrupting the Lions' offensive rhythm. The turning point came in the second quarter when Williams' interception shifted momentum and allowed Buffalo to extend their lead, ultimately sealing the victory. The Lions struggled to respond, leaving them to regroup as they head into the next week.