In a decisive Week 6 showdown, the Detroit Lions topped the Buffalo Bills with a final score of 42-24, solidifying their position as contenders in the 2028 season. The Lions' impressive performance kept them in the playoff conversation, while the Bills struggled to find their rhythm on both sides of the ball. Bryce Underwood led the offensive charge for Detroit, throwing for 244 yards and four touchdown passes, showcasing his ability to connect with the Lions' receiving corps. Meanwhile, Khalil Shakir was the standout for Buffalo, racking up 133 receiving yards, though his efforts fell short of igniting a comeback. James Cook III added a solid ground game with 62 rushing yards, but it wasn’t enough to match the Lions' offensive firepower. Defensively, the Lions made crucial plays that shifted the momentum of the game, with Carlton Davis III snagging an interception to disrupt a promising Bills drive. Brian Branch anchored the Lions' defensive unit with three total tackles, while Landon Jackson’s lone sack for the Bills provided some brief hope. The turning point came when the Lions scored back-to-back touchdowns in the second quarter, leaving Buffalo scrambling to keep pace.