In a decisive Week 4 matchup, the Kansas City Chiefs topped the San Francisco 49ers with a final score of 31-14. With both teams looking to establish momentum early in the 2028 season, this victory places the Chiefs in a strong position moving forward. Chiefs quarterback Patrick Mahomes delivered a stellar performance, throwing for 382 yards and three touchdowns, showcasing his elite playmaking ability. Rashee Rice emerged as his favorite target, racking up 148 receiving yards, while the Chiefs' offense consistently moved the chains and found the end zone. Defensively, Kansas City made key plays that turned the tide in their favor. Trey White contributed with a crucial sack, and Nohl Williams sealed the game with an interception, stifling any chance of a 49ers comeback. The Chiefs' ability to create turnovers and pressure the quarterback proved pivotal, as they maintained control throughout the contest.