In a commanding Week 1 showdown, the New York Jets topped the San Francisco 49ers with a final score of 42-21, marking a strong start to the 2028 season. The Jets showcased their offensive prowess, while the 49ers struggled to contain their momentum throughout the game. Arch Manning led the Jets with a stellar performance, throwing for 291 yards and contributing significantly to the team's scoring efforts. Garrett Wilson was his top target, racking up 93 receiving yards, while the Jets' ground game kept the pressure on San Francisco's defense. Despite Brock Purdy's two touchdown passes for the 49ers and Christian McCaffrey's 92 rushing yards, the Jets' offensive execution proved too much to handle. Defensively, the Jets were able to stifle the 49ers at key moments, with Nahshon Wright contributing half a sack, though no standout performances were recorded on that side of the ball. The game shifted decisively in the Jets' favor during the second quarter, where they outscored the 49ers 21-7, creating a lead that San Francisco could not overcome. Overall, the Jets' balanced attack and defensive resilience were critical in securing their victory.