In a commanding performance, the Miami Dolphins defeated the San Francisco 49ers 37-10 in Week 2 of the 2026 season. This victory not only boosts Miami's confidence but also establishes them as a formidable contender early in the year, while the 49ers will look to regroup after a disappointing outing on their home turf. Malik Willis shone as the standout offensive player for the Dolphins, throwing for 228 yards and three touchdowns, showcasing his ability to lead the team effectively. His connection with receiver Caleb Douglas, who amassed 75 receiving yards, further solidified Miami's aerial attack. The Dolphins' offense was relentless, consistently putting points on the board and leaving the 49ers struggling to keep pace. Defensively, Miami made crucial plays, with Michael Taaffe leading the way with six total tackles and Chris Johnson contributing with an interception. The turning point came midway through the second quarter when Willis threw his second touchdown pass, pushing the Dolphins ahead 21-3 and deflating the 49ers' hopes of a comeback. San Francisco's Mykel Williams registered two sacks, but it wasn't enough to overcome the Dolphins' overwhelming offensive display.