In a decisive matchup for playoff positioning, the Detroit Lions topped the San Francisco 49ers 21-10 in Week 17 of the 2027 season. With both teams vying for a stronger postseason berth, the Lions showcased their depth and execution to secure the victory. Haynes King led the Lions' offense with two passing touchdowns, while Jahmyr Gibbs dominated on the ground, racking up 109 rushing yards. Micah Smith of the 49ers put up impressive numbers with 236 passing yards, but it wasn't enough to keep pace with Detroit's balanced attack. Defensively, the Lions were relentless, with Troy Andersen leading the way with six total tackles. Alim McNeill added a sack, while Craig Woodson's interception proved pivotal, halting a potential scoring drive from the 49ers. The turning point came in the third quarter when Woodson's pick set the tone for Detroit, allowing them to maintain control and ultimately seal the win.