In a dominating performance, the Dallas Cowboys topped the San Francisco 49ers 56-21 in Week 10 of the 2026 season. With playoff positioning on the line, Dallas showcased their offensive prowess, firmly establishing themselves as a contender as they look to build momentum in the latter half of the season. Quarterback Dak Prescott was sensational, throwing for 287 yards and an impressive six touchdowns, leading the charge for the Cowboys. Running back Jaydon Blue added a powerful ground game with 158 rushing yards, while CeeDee Lamb torched the 49ers' secondary for 224 receiving yards, making for a lethal offensive trio that kept San Francisco on their heels all night. Defensively, the Cowboys were effective in limiting the 49ers' scoring opportunities, with Malachi Lawrence contributing a sack to the effort. Although the 49ers' Malik Mustapha recorded five total tackles and Deommodore Lenoir snagged two interceptions, it was the Cowboys' relentless pressure and opportunistic defense that turned the tide of the game. The defining moment came in the second quarter when Prescott connected with Lamb for a 75-yard touchdown, which helped Dallas pull away and set the tone for the rest of the match.