In a commanding season opener, the Arizona Cardinals topped the Los Angeles Chargers 37-3, making a strong statement as they embark on the 2026 campaign. With both teams eager to set the tone for the season, the Cardinals demonstrated their dominance right out of the gate. Jacoby Brissett led the charge for Arizona, racking up 288 passing yards and throwing three touchdown passes. Tyler Allgeier contributed significantly on the ground with 89 rushing yards, while Marvin Harrison Jr. shined in the receiving game, tallying 124 yards through the air. The Cardinals' offensive efficiency was evident as they consistently moved the ball and found the end zone. On the defensive side, the Cardinals stifled the Chargers' offense, with Josh Sweat recording 1.5 sacks and Will Johnson snagging an interception. The turning point came early in the second quarter when Johnson's pick set up another touchdown drive, pushing Arizona's lead to 24-3. With their defense controlling the game and the offense firing on all cylinders, the Cardinals left no doubt in their emphatic victory.