Cardinals at 49ers

Franchise Hub Beat · 3d ago

In a thrilling season opener, the Arizona Cardinals narrowly defeated the San Francisco 49ers with a final score of 34-28. Both teams were eager to start the 2027 season on a high note, but it was the Cardinals who emerged victorious, showcasing their offensive prowess and resilience in a tightly contested matchup.

The Cardinals' offensive standout was De'Von Achane, who racked up an impressive 183 rushing yards, proving to be a key force in their ground game. Meanwhile, Joe Burrow of the 49ers threw for 347 yards and three touchdowns, keeping San Francisco in the game until the final whistle. Jordan Johnson also had a stellar performance, leading all receivers with 157 yards, highlighting the 49ers' aerial attack.

On the defensive side, the Cardinals managed to make critical plays, with Cooper DeJean snagging an interception that shifted momentum in their favor. The turning point came late in the fourth quarter when Achane broke free for a long touchdown run, solidifying Arizona's lead and ultimately sealing the victory despite a late surge from Burrow and the 49ers. Both teams showed promise, but it was the Cardinals who held off the 49ers to secure the win.