In a dominating performance, the Indianapolis Colts defeated the New England Patriots 49-11 in Week 6 of the 2027 season. This victory not only solidifies the Colts' strong standing in the league but also raises questions about the Patriots' struggles as they seek to turn their season around. Baker Mayfield was the star of the show, throwing for four touchdowns and leading the Colts' explosive offense. Meanwhile, Drake Maye put up impressive numbers for the Patriots with 334 passing yards, but it wasn't enough to keep pace with the Colts. On the receiving end, Ja'Kobi Lane shined brightly with 188 yards, showcasing his ability to stretch the field. Defensively, the Colts were relentless, with Laiatu Latu recording two sacks and CJ Allen snagging an interception to halt any momentum the Patriots attempted to build. The turning point came early in the second half when the Colts' defense forced a turnover that led to a quick touchdown, allowing them to pull away and secure the victory decisively. Cam Taylor-Britt led the team with five tackles, helping to stifle the Patriots' offensive efforts throughout the game.