In a commanding performance, the Houston Texans defeated the Indianapolis Colts 52-13 in Week 3 of the 2026 season. The Texans showcased their dominance, leaving no doubt about their ambitions this year as they continue to solidify their standing in the league. C.J. Stroud led the charge for Houston, throwing for an impressive 411 yards and six touchdown passes, showcasing his ability to dissect the Colts' defense. Woody Marks complemented the aerial assault with a strong ground game, racking up 124 rushing yards, while Tyreek Hill was a favorite target, hauling in 149 receiving yards. Together, the trio created a potent offensive threat that the Colts simply could not contain. Defensively, the Texans were just as effective, particularly with Derek Stingley Jr. making a game-changing impact with three interceptions. The turning point came when Stingley picked off a pass in the first half, setting up another touchdown and extending Houston's lead to an overwhelming margin. Despite Mack Wilson Sr.'s solid efforts for the Colts, with six tackles and a sack, it was clear that the Texans' defense was relentless, contributing significantly to the lopsided scoreline.