In a dominant performance, the Denver Broncos topped the San Francisco 49ers 37-14 in Week 4 of the 2026 season. With this win, the Broncos solidify their position in the playoff race, showcasing their offensive prowess and defensive resilience throughout the game. Leading the charge for the Broncos was RJ Harvey, who exploded for 258 rushing yards, consistently breaking tackles and finding gaps in the 49ers' defense. Quarterback Bo Nix contributed with 150 passing yards, while the 49ers' Brock Purdy managed just one touchdown pass, highlighting the contrasting offensive efforts. Ricky Pearsall was the standout receiver for San Francisco, finishing with 73 receiving yards but unable to make a significant impact on the scoreboard. The Broncos' defense played a crucial role in the outcome, with Frankie Luvu notching a sack and Ji'Ayir Brown securing an interception for San Francisco. The turning point came early in the second half when the Broncos scored two quick touchdowns, shifting the momentum decisively in their favor. With the 49ers unable to respond effectively, Denver maintained control for the remainder of the game, sealing a comprehensive victory.