In a commanding performance, the San Francisco 49ers topped the Los Angeles Chargers 35-14 in Week 15 of the 2026 season, solidifying their playoff position. With postseason implications on the line, the 49ers showcased their dominance on both sides of the ball, effectively controlling the tempo throughout the game. Christian McCaffrey was the standout star for San Francisco, racking up an impressive 217 rushing yards, while De'Zhaun Stribling contributed significantly with 89 receiving yards. Chargers quarterback Justin Herbert threw for 180 yards and two touchdowns, but his efforts were not enough to keep pace with the 49ers' relentless offense. Defensively, the 49ers were a force to be reckoned with, led by Nick Bosa’s three sacks and Tre'von Moehrig’s two interceptions, which proved pivotal in stifling the Chargers' momentum. The turning point came in the second quarter when Moehrig intercepted Herbert, setting up a quick touchdown that widened the gap and put the 49ers firmly in control. San Francisco's defense not only limited the Chargers' scoring opportunities but also created crucial turnovers that shifted the game's dynamics.