In a tightly contested matchup, the San Francisco 49ers narrowly defeated the Los Angeles Rams, 21-17, in Week 14 of the 2026 season. With playoff implications on the line, both teams fought hard, but it was the 49ers who managed to secure the crucial victory at home. Quarterback Mac Jones led the way for San Francisco, throwing for two touchdowns, while Matthew Stafford of the Rams put up 197 passing yards, showcasing his ability to move the ball downfield. Kyren Williams was a standout in the backfield for Los Angeles, rushing for 92 yards, while Mason Tipton contributed significantly with 70 receiving yards, keeping the Rams competitive throughout the game. Defensively, Dre Greenlaw made a significant impact for the 49ers with seven tackles and two sacks, disrupting the Rams' offensive rhythm. The game's turning point came in the fourth quarter when Greenlaw's second sack led to a fumble that shifted momentum back to San Francisco, allowing them to maintain their lead and ultimately seal the game. Meanwhile, Quentin Lake's two interceptions for the Rams kept the pressure on, but it wasn't enough to turn the tide in their favor.