In a tightly contested matchup, the New England Patriots narrowly defeated the Buffalo Bills 24-21 in Week 4 of the 2026 season. With both teams vying for momentum early in the season, the stakes were high as they battled for supremacy in the division. Patriots quarterback Drake Maye delivered a standout performance, throwing for 246 yards and three touchdowns, showcasing his ability to command the offense. Meanwhile, TreVeyon Henderson emerged as his primary target, racking up 134 receiving yards and making crucial catches that helped secure the victory. On the ground, James Cook III led the Bills with 48 rushing yards but struggled to find the end zone. Defensively, the Patriots managed to contain the Bills' offense just enough to secure the win, although the Bills' C.J. Gardner-Johnson made his presence felt with a sack and an interception. The turning point came late in the fourth quarter when Maye connected with Henderson for a touchdown that put the Patriots ahead for good. Despite a valiant effort from the Bills' defense, they couldn't overcome the Patriots' late-game surge.