In a decisive showing to kick off the 2026 season, the Houston Texans topped the Buffalo Bills with a commanding final score of 49-21. The victory not only sets a strong tone for Houston but also underscores their offensive firepower as they look to contend this year. Leading the charge for the Texans was quarterback David Carr, who threw for an impressive 355 yards and four touchdowns, showcasing his ability to connect with receivers under pressure. Jerome Mathis emerged as Carr's go-to target, racking up 223 receiving yards, while Buffalo's Willis McGahee shone on the ground with a staggering 240 rushing yards, but it wasn't enough to match Houston's offensive onslaught. Defensively, the Texans were relentless, with Dunta Robinson leading the team with four tackles and DeMeco Ryans making a significant impact by snagging two interceptions. The turning point came in the second quarter when Ryans' interceptions shifted momentum firmly in favor of Houston, allowing them to build an insurmountable lead that the Bills could never recover from.